Publications from CP Lab
 
  • Ortiz FC, Puebla C. (2019). Pannexin1-based channels activity as a novel regulator of multiple sclerosis progressionNeural Regeneration Research. 15(1):65-66. doi: 10.4103/1673-5374.264450


     
  • Cea LA, Balboa E, Vargas AA, Puebla C, Brañes MC, Escamilla R, Regueira T, Sáez JC. (2019). De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemiaBBA- Molecular Basis of Disease. 1865(10):2765-2773. doi: 10.1016/j.bbadis.2019.06.014.


     
  • Cisterna BA, Arroyo P, Puebla C. (2019). Role of connexin-based gap junction channels in communication of myelin sheath in Schwann cellsFrontiers in Cellular Neuroscience. 13:69. doi: 10.3389/fncel.2019.00069.


     
  • Puebla C, Retamal MA, Acuña R, Sáez JC. (2017)Regulation of connexin-based channels by fatty acids. Frontiers in Physiology 8:11. doi: 10.3389/fphys.2017.00011

     
Previous publications (pregraduate, postgraduate and Postdoctoral training)
  • Cisterna BA, Vargas AA, Puebla C, Sáez JC. (2016). Connexin hemichannels explain the ionic imbalance and lead to atrophy in denervated skeletal musclesBBA - Molecular Basis of Disease 1862(11):2168-2176. 

     
  • Puebla C, Cisterna BA, Salas DP, Delgado-Lopez F, Lampe PD, Sáez JC. (2016). Linoleic acid permeabilizes gastric epithelial cells by increasing connexin43 levels in the cell membrane via a GPR40- and Akt-dependent mechanismBBA - Molecular and Cell Biology of Lipids 1861(5):439-448. doi: 10.1016/j.bbalip.2016.02.002

     
  • Cea LA, Balboa E, Puebla C, Vargas AA, Cisterna BA, Regueira T, Sáez JC. (2016). Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels. BBA - Molecular Basis of Disease 1862(10):1891-1899. doi: 10.1016/j.bbadis.2016.07.003.

     
  • Cea L, Puebla C, Cisterna BA, Escamilla R, Vargas AA, Frank M, Martinez-Montero P, Prior C, Molano J, Esteban-Rodríguez I, Pascual I, Gallano P, Lorenzo G, Pian H, Barrio LC, Willecke K, Sáez JC. (2016). Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis. Cellular and Molecular Life Sciences 73(13):2583-2599. doi: 10.1007/s00018-016-2132-2

     
  • Riquelme MA, Cea LA, Vega JL, Puebla C, Vargas A, Shoji KF, Subiabre M, Sáez JC. (2015). Activation of P2 receptors by ATP released via pannexin hemichannels induces the myogenic commitment acquisition of C2C12 reserve cells. Frontiers in Cell and Developmental Biology 3:25. doi: 10.3389/fcell.2015.00025

     
  • Salas D, Puebla C, Lampe PD, Sáez JC. (2015). Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition. BBA- Molecular Basis of Disease 1852 (7):1268-1277. doi: 10.1016/j.bbadis.2015.03.004

     
  • Contador D, Ezquer F, Espinosa M, Arango-Rodriguez M, Puebla C, Sobrevia L, Conget P. (2015). Dexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells. Exp Biol Med (Maywood) 240(9): 1235-1246. doi: 10.1177/1535370214566565

     
  • Cea LA, Cisterna BA, Puebla C, Frank M, Figueroa X, Cardozo C, Willecke K, Latorre R, Sáez JC. (2013). De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy. Proc Natl Acad Sci USA 110(40):16229-16234. doi: 10.1073/pnas.1312331110

     
  • Cea LA, Riquelme MA, Cisterna BA, Puebla C, Vega JL, Rovegno M, Sáez JC. (2012). Connexin- and pannexin-based channels in normal skeletal muscles and their possible role in muscle atrophy. Journal of Membrane Biology 245(8):423-436.
     

     
  • Salomón C, Westermeier F, Puebla C, Arroyo P, Guzmán-Gutiérrez E, Pardo F, Leiva A, Casanello P, Sobrevia L. (2012). Gestational diabetes reduces adenosine transport in human placental microvascular endothelium, an effect reversed by insulin. Plos ONE 7(7): e40578. doi:10.1371/journal.pone.0040578.
     
  • Guzmán-Gutiérrez E, Abarzúa F, Belmar C, Nien JK, Arroyo P, Salomón C, Westermeier F, Puebla C, Leiva A, Casanello P, Sobrevia L. (2011). Are adenosine and insulin functionally linked in vascular endothelial dysfunction in gestational diabetes mellitus?. Current Vascular Pharmacology 9(6):750-762.
     
  • Westermeier F, Salomón C, González M, Puebla C, Guzmán-Gutiérrez E, Casanello P, Sobrevia L. (2011). Differential modulation of adenosine transport by insulin in human umbilical vein endothelial cells from gestational diabetes mellitus. Diabetes 60 (6):1677-1687.
     
  • Sobrevia L, Abarzúa F, Nien JK, Salomón C, Westermeier F, Puebla C, Cifuentes F, Guzmán-Gutiérrez E, Leiva A, Casanello P. (2011). Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes. Placenta 32, Supl 2: S159-164.
     
  • Farías M, Puebla C, Westermeier F, Jo MJ, Pastor-Anglada M, Casanello P, Sobrevia L. (2010). Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving  transcription factor complex hCHOP-C/EBPa in human umbilical vein endothelial cells from gestational diabetes. Cardiovascular Research. 86 (1): 45-54.
     
  • Westermeier F*, Puebla C*, Vega JL, Farías M, Escudero C, Casanello P, Sobrevia L. (2009). Equilibrative nucleoside transporters in fetal endothelial dysfunction in diabetes mellitus and hyperglycaemia. Current Vascular Pharmacology 7 (4): 435-449.
     
  • Escudero C, Puebla C, Westermeier F, Sobrevia L. (2009). Potential cell signalling mechanisms involved in differential placental angiogenesis in mild and severe pre-eclampsia. Current Vascular Pharmacology 7 (4): 475-485.
     
  • Vega JL, Puebla C, Vásquez R, Farías M, Alarcon J, Pastor-Anglada M, Krause B, Casanello P, Sobrevia L. (2009). TGF-β1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium. Cardiovascular Research 82 (3): 458-467.
     
  • Puebla C, Farías M, González M, Vecchiola A, Aguayo C, Krause B, Pastor-Anglada M, Casanello P, Sobrevia L. (2008). High D-glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium. Journal of Cellular Physiology 215 (3): 645-656.
     
  • Farías M, San Martín R, Puebla C, Pearson JD, Casado J, Pastor-Anglada M, Casanello P, Sobrevia L. (2006). Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endothelium from gestational diabetes. Journal of  Cellular Physiology 208 (2):451-460.